From Tucuman to the Bolivian border, you'll pass through a mind-blowing array of ecosystems and cultures, gawking at the majesty of the Andes while staying in easy-to-ride valleys. Visit the deserted Inca ruins of Quilmes before heading into the wine country around Cafayate. Salta, the biggest city in the region, is Argentina's best-preserved colonial city and heart of its native culture. Also on the route are Jujuy and Purmamarca, with its famous seven-coloured hill. Best in fall or spring.
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